How to Change the Passive Inlet Valve (PIV) on a 1260 Isocratic or Quaternary Pump

Created by Damian O'Neill over 2 years ago | Last modified by Carlos Vargas 1 month ago

This Information Applies To: Agilent 1260 Isocratic (G1310B) Quaternary (G1311B) Pumps.

Issue

Required when:

The inlet valve is defective.
The pressure or leak test in Lab Advisor suggests the inlet valve may require replacement.
A large increase in pressure ripple is observed.

Steps to follow

Tools Required:

8710–1924 - Open-end wrench 14 mm
5067–5688 - Torque wrench, 1 - 25 Nm with 14 mm wrench
Pair of tweezers or small flat blade screwdriver

Parts Required:

G1312-60066 - Passive Inlet Valve 1220/1260

Warning: This procedure risks exposure to hazardous, toxic, or flammable solvents and reagents. Wear appropriate PPE as described in the material handling and safety data sheet supplied by the chemical vendor, and always follow good laboratory practice.

1. Remove the pump front cover.

2. If possible, raise the solvent filters in each solvent bottle connect to the pump above the level of solvent in the bottle. This will minimize solvent leaking from the solvent tubes while performing this maintenance.

3. Disconnect the solvent inlet tube from the inlet valve. Be aware that solvents might leak out of the tube, so use gloves and lab wipes to catch any spills.

4. Using a 14 mm wrench, loosen the passive inlet valve and remove the valve from the pump head (Figure 1).

Figure 1. Disconnect the solvent inlet tube (1) and remove the PIV (2) from the pump head.

5. Insert the new inlet valve into the pump head and tighten the valve using a torque wrench to 12 Nm (Figure 2).

6. Reconnect the solvent inlet tube to the passive inlet valve.

Figure 2. Install the new PIV and reconnect the solvent inlet tube.

7. Reinstall the front cover.

If possible, run a system pressure test with the outlet of the purge valve blanked off using the appropriate blanking nut (Part No. 01080–83202). This checks that the pump flow path is pressure tight to a pressure higher than your application requires.

Cause: If old or aged acetonitrile is left in the outlet ball valve, the ball inside the valve can stick open or closed causing pressure and flow issues. Always flush pumps after use according to instructions given in the pump user manual.