Collection of LC (HPLC) Resources

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Here is a "best of" collection of links to manuals and tools for HPLC on, for other instruments refer to Collection of Support Documents on


Collection of LC (HPLC) Resources




LC Troubleshooting


LC Hardware and Miscellaneous Documents

LC Hardware Manual LinksCollection of current LC hardware manuals
LC Firmware/ToolsDownload link  LC-Firmware and tools including the famous Lab Advisor
Agilent 1100/1200/1290 Series Firmware UpdatesInformation  Firmware Update
LC Firmware Background informationBackground information for Firmware
HPLC Maintenance VideosStep by step videos on 1260 LC maintenance on Youtube
1100 Series LC and LC/MS Maintenance VideosStep by step videos on 1100 LC maintenance


LC Application resources

LC HandbookLC application primer

Solutions for Preparative HPLC - Application Compendium

Application compendium for preparative LC
Optimize binary pumpOptimization of LC and LC/MS
HPLC Separation FundamentalsBasics of LC separation
New to HPLC Tips for Avoiding Beginner PitfallsEssentials for new LC users
LC Troubleshooting Series Retention Time ShiftsBest practice to troubleshoot retention time shifts
LC Column Troubleshooting – Isolating the Source of the ProblemBest practice to troubleshoot column related problems
Best practice fundamentals for using an LC-systemBest practice fundamentals for using an LC-system

Sample preparation fundamentals for chromatography

Handbook covering many different sample preparation technologies
Agilent LC Application finderApplication notes selection tool
Principles and Practical Aspects of Preparative Liquid Chromatography A primer for principles in preparative HPLC
Your reference guide to the Analysis of biopharmaceuticals and biomoleculesAgilent BioHPLC column selection guide
Method Transfer analytical HPLC to preparative HPLCApplication note for method transfer
Solutions for preparative HPLCApplication compendium
How to set up an LC method screening campaign with Method Scouting WizardAgilent Method Scouting Wizard Tutorial Series on Youtube

Agilent Interact (Virtual LC Simulation)


LC Catalogs and Parts Finder


Agilent Collection of Columns, Supplies, and Standards Resources


InfinityLab LC Supplies catalogConsumables catalog
Agilent LC Capillary Finder

LC capillary search tool, more comprehensive overview on current LC

capillary portfolio in LC supplies catalog.

Agilent Vial Selector / FinderSelection tool for vials, caps and septa fitting your application
Agilent LC Column finderFind the best column for your application
Agilent Filter Selector / FinderFind the best filter for your application


"How-to" documents in the Agilent Community prepared from your Agilent Service Engineers


How to perform a cold startStep for step manual to perform a cold start


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