Algae Growth in HPLC Systems

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The presence of algae in HPLC systems can cause a variety of problems that

may be incorrectly diagnosed as instrument or application problems. Algae

grow in aqueous media, preferably in a pH range of 4-8. Their growth is

accelerated by buffers, for example phosphate or acetate. Since algae grow

through photosynthesis, light will also stimulate their growth. Even in distilled

water small-sized algae grow after some time.