Characterization of Styrene-Acrylonitrile Copolymers Using Comprehensive 2D-LC Investigation of Two Mutually Dependent Distributions

Version 2

    Application Note

    Energy and Chemicals



    Synthetic polymers are complex mixtures with distributions in various molecular characteristics such as molecular weight and chemical composition. For a polymer with distributions in two molecular characteristics, full characterization can only be achieved using two-dimensional separation. This Application Note shows the analysis of styrene-acrylonitrile copolymers (SAN) using comprehensive two-dimensional liquid chromatography with interaction chromatography in the first dimension and fast size exclusion chromatography (SEC) in the second dimension. In the first dimension, separation according to the acrylonitrile content (chemical composition) is achieved, and the second-dimension SEC separation enables determination of the molecular weight distributions of the SAN with different acrylonitrile contents


    Publication number: 5991-6899EN

    Publication Date: April 1, 2016