Of the 52.8 million world-wide deaths in 2010, approximately two-thirds were caused by chronic diseases, mainly cardiovascular disease (> 15 million) and cancer (> 7 million) . Thus, it is reasonable to ask whether chronic diseases are attributable to genetic factors, exposures, or some combination of the two. Data compiled by the Swedish Family-Cancer Database indicate that genetic (G) risks for 15 common cancers were 10% or less . This suggests that approximately 90% of cancer risks result from exposures (E) or G×E interactions.
Publication number: 5991-3418EN
Publication Date: September 15, 2015