Using the Blood Exposome to Discover Causes of Disease

Version 1

    Application Note

    Clinical Research

     

    Abstract

    Of the 52.8 million world-wide deaths in 2010, approximately two-thirds were caused by chronic diseases, mainly cardiovascular disease (> 15 million) and cancer (> 7 million) [1]. Thus, it is reasonable to ask whether chronic diseases are attributable to genetic factors, exposures, or some combination of the two. Data compiled by the Swedish Family-Cancer Database indicate that genetic (G) risks for 15 common cancers were 10% or less [2]. This suggests that approximately 90% of cancer risks result from exposures (E) or G×E interactions.

     

    Publication number: 5991-3418EN

    Publication Date: September 15, 2015

     

    http://www.agilent.com/cs/library/technicaloverviews/public/5991-3418EN.pdf