A New Approach to the Analysis of Chlorinated Paraffins by GC/Q-TOF (ASMS 2015, Gao et al.)

Version 1

    Presented as the 2015 meeting of the American Society for Mass Spectrometry (ASMS) meeting.

    by Wei Gao(1) , Yawei Wang(1) , Wenwen Wang(2)

    (1): Research Center for EcoEnvironmental Sciences, Beijing, China;

    (2) Agilent Technologies Company Limited, Beijing, China

     

    Introduction:

    Chlorinate paraffins (CPs), also known as polychlorinated n-alkanes, have been used in large amounts for decades in commercial products. The commercial CPs mixtures can be divided into different species:

    • short-chain chlorinate paraffins C10-C13 (SCCPs)
    • medium-chain chlorinated paraffins C14-C17 (MCCPs)
    • long-chain chlorinated paraffins C20-C30 (long)

    CP mixtures are extremely complex, with over 10's of thousands of congeners and isomers, which makes separation by GC very challenging. NCI-LRMS is well-suited for routine analysis, however it is subject to the interferences and overlap from other polychlorinated pollutants and CPs with the same nominal mass. In addition to the need of optimization on sample extraction and clean-up procedures, the interferences from mass overlap between SCCP and MCCP congeners are also to be addressed. In this study, due to sensitivity and separation challenge, an analytical pproach based on NCI-GC-QTOF has been developed.

     

    (Original source: http://www.agilent.com/cs/library/posters/public/ASMS_2015_TP_113.pdf  )