Reduce Cost of Pesticide Residue Analysis-An Application for Mini-QuEChERS with GC/MS/MS and a High-Efficiency Source

Version 1

    Application Note

    Food Testing and Agriculture

     

    Abstract

    Laboratories responsible for ensuring food safety seek to reduce the cost per analysis without compromising the accuracy and reliability of their results. A promising approach involves miniaturization of the QuEChERS extraction method and the use of smaller sample injection volumes. We found cost savings of >40% due to reductions in solvent, sorbent, and labeled ISTD. Use of a high-efficiency source and only 0.5 µL injection further reduces sample cost through decreased maintenance, while still enabling lower limits of quantitation (LOQs). In carrot, tomato, and celery, recovery-based LOQs for 86 to 90% of the 126 pesticides analyzed were 1 ng/g, and 95 to 98% of the pesticides had LOQs ~5 ng/g. This is half the accepted default maximum residue limit (MRL), of 10 ng/g. Challenging captan and folpet residues were quantified at ~5 and 1 ng/g, respectively, by using commercially available ISTDs captan-d6 and folpet-d4 for only $0.04 per sample.

     

    Publication number: 5591-5905EN.pdf

    Publication Date: July 8, 2015

     

    http://www.agilent.com/cs/library/applications/5991-6069EN.pdf