Food Testing and Agriculture
Agilent Bond Elut Enhanced Matrix Removal—Lipid (EMR—Lipid) is the next generation of sample preparation products, and is used in convenient, dispersive solid phase extraction (dSPE) for highly selective matrix removal without impacting analyte recovery, especially for high-fat samples. This study demonstrates the application of this novel product for the analysis of 23 GC-amenable pesticides in avocado by GC/MS/MS. The procedure involves a QuEChERS AOAC extraction followed by EMR—Lipid dSPE and polish salts. EMR—Lipid provides far superior matrix removal by weight, GC/MS full scan, and matrix effect determination when compared to C18/PSA and zirconia-based sorbents. Furthermore, less matrix is introduced into the analytical flow path. The data also demonstrate dramatically improved reproducibility for the analytes over 100 injections relative to C18/PSA and especially zirconia, which experience significant response deviations. EMR—Lipid is highly selective for lipids and does not negatively affect analyte recovery. Analyte recoveries are high and precision is outstanding. This work demonstrates that EMR—Lipid dSPE fits into a QuEChERS workflow and delivers fast, robust, and effective sample preparation with the most complete matrix removal available for multiresidue analysis of pesticides in avocado.
Publication number: 5991-6097EN.pdf
Publication Date: August 21, 2015